glutathione peroxidase lipid peroxides 2 - an overview Lipid Peroxidation Adds Fuel to

Genes Dev 2010

doi: 10.31467/uluaricilik.527986 54 PuccaMBCerniFAOliveiraISJenkinsTPArgemLSrensenCVet al

5.4 Western diet The dietary structure of western diet pattern represented by western developed countries is characterized by high energy food intake, high protein, saturated fat, refined cereals, sugar, alcohol and salt, and low intake of omega-3 fatty acids, fruits and vegetables, thus has the diet pattern of three highs of high calories, high fat and high protein

More importantly, epigenetic modifications are essential regulatory mechanisms for biological processes in the body, and recent studies have shown that ferroptosis is regulated by various epigenetic modifications, including DNA methylation, the RNA m 6 A modification and protein methylation[3, 8, 98, 99]

All the previous examples of methyltransferases discovery started with genome mining and biosynthetic gene cluster identification (Table 1)

Supplementary information Supplementary Tables 14 and Note